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KMID : 0881720170320030234
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Journal of Food Hygiene and Safety
2017 Volume.32 No. 3 p.234 ~ p.242
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Changes in Antioxidant and Antiobesity Activities of Cirsium setidens Nakai Ethanolic Extract Depending on Different Harvest Time
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Cho Bong-Yeon
Lee Jin-Ha
Choi Sun-Il
Jung Tae-Dong
Choi Seung-Hyun
Ra Moon-Jin
Kim Sun-Young
Kang Il-Jun
Han Kyoung-Chan
Lee Ok-Hwan
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Abstract
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This study was conducted to provide basic data of Cirsium setidens Nakai in different harvest time that will be applied for development of functional foods and ingredients. We investigated pectiolinarin and pectolinarigenin content, total flavonoids content and antioxidant effects (DPPH radical scavenging activity and ORAC assay) of C. setidens Nakai. Our results showed that the pectolinarin and total flavonoids contents of C. setidens Nakai in harvesting time ranged from 43.13 ± 0.22 to 95.65 ± 0.34 mg/g and from 32.81 ± 1.68 to 40.43 ± 0.35 mg rutin equivalent (RE)/g, respectively. The DPPH radical scavenging activity of C. setidens Nakai did not show differences in harvesting time. The oxygen radical absorbance capacity (ORAC) value was highest in August (2016) extracts (827.72 μmole TE/g). In addition, C. setidens Nakai exthanolic extract in harvesting time did not show any cytotoxicity up to 200 μg/mL. During adipocyte differentiation, C. setidens Nakai extract in harvesting time significantly inhibited lipid accumulation and ROS production, compared with the controls. These results suggest that C. setidens Nakai extract could be considered as a non-toxic natural resources of functional food ingredients and natural antioxidants.
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KEYWORD
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C. setidens Nakai , Pectolinarin , Antioxidant Activity , Antiobesity
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